What is the maximum approved daily dose of orlistat for adults?

What is the maximum approved daily dose of orlistat for adults?

• A. 60 mg three times daily with meals
• B. 120 mg three times daily with meals
• C. 80 mg twice daily
• D. 100 mg four times daily

Answer: (B)

Orlistat dosing is tied to meals because it blocks fat absorption; the approved adult regimen is to take 120 mg with each main meal that contains fat, up to three meals per day. This sets the maximum daily dose at 360 mg (120 mg × 3). If a meal has little or no fat, you skip that dose to avoid unnecessary exposure and potential side effects. Other dosing patterns don’t meet the approved guidance: taking smaller per-meal doses results in a lower daily total, while regimens with more frequent dosing or larger per-dose amounts don’t align with the established maximum. The key point is that the highest safe total for adults is 360 mg per day, given as 120 mg with each fat-containing meal, up to three meals.

Orlistat dosing is tied to meals because it blocks fat absorption; the approved adult regimen is to take 120 mg with each main meal that contains fat, up to three meals per day. This sets the maximum daily dose at 360 mg (120 mg × 3). If a meal has little or no fat, you skip that dose to avoid unnecessary exposure and potential side effects. Other dosing patterns don’t meet the approved guidance: taking smaller per-meal doses results in a lower daily total, while regimens with more frequent dosing or larger per-dose amounts don’t align with the established maximum. The key point is that the highest safe total for adults is 360 mg per day, given as 120 mg with each fat-containing meal, up to three meals.